PREFACE: IS HETEROCYCLIC CHEMISTRY BORING?

Why Mathematics is Boring

Storytellers have many strategies for luring in their audience and keeping them interested. These include standardized narrative structures, vivid characters, breaking down long stories into episodes, and subtle methods of reminding the readers of facts they may have forgotten. The typical style of writing mathematics systematically avoids these strategies, since the explicit goal is “proving a...

Heterocyclic amines: chemistry and health.

Heterocyclic amines (HAs) occur at the ppb range in foods. Most of them demonstrate potent mutagenicity in bacteria mutagenicity test, and some of them have been classified by the International Agency for Research on Cancer as probable/possible human carcinogens. Their capability of formation even during ordinary cooking practices implies frequent exposure by the general public. Over the past 3...

Tele-substitutions in Heterocyclic Chemistry.

Particular and rare examples of aromatic nucleophilic substitution are described as tele-substitution. Usually strong nucleophiles are involved and the entering group is introduced at a position distant from the expected leaving group. Examples of tele-substitution in various heteroaromatic systems are presented.

Introduction of Medicinal Chemistry & Heterocyclic Compounds

Aromaticity as a cornerstone of heterocyclic chemistry.